Khanyisile Kweyama is former : CEO of BUSA, in this role she represented business on the BRICS Business Council, Nedlac, Presidential Working Group , She was appointed to the NPC in 2015, she is former Chairperson of Brand SA She served as the Executive Director for Anglo American, as well as on the boards of Kumba Iron Ore, Anglo American Platinum. While serving as ED of Anglo SA She was chairperson of the Zimele Enterprise Development Fund. She was elected Vice President of the Chamber of Mines of SA in 2013 - 2014.Khanyisile was recognized as one of the most influential women in business and the mining sector and as one of the 100 women to watch globally by the FTSE 100.

Kweyama served as an executive at Altech, Barloworld and Anglo American Platinum. She serves on the Telkom Board and is the chairperson of the Social & Ethics Committee. She studied at the University of Fort Hare before going to exile. She studied Management in Virginia in the , USA and furthered her studies at Wits School of Management , obtaining a PDM (management) in 1996 .

Ms Kweyama also serves on the boards of United Manganese of Kalahari and Steinhoff Internaional Holdings.